Treatment for high cholesterol includes changes in diet, exercise, smoking cessation and sometimes medications.
But, can supplements help?
Key Takeaways
Many supplements are marketed to help reduce cholesterol levels.

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Making changes to your diet and activity level are much more effective and potentially safer than taking a supplement.
Taking certain supplements can be dangerous, especially if they interfere with your medications or cause unwanted side effects.
Dietary cholesterol is found in animal foods, such as dairy products and meat.
In this article, you will learn about four supplements you should not take if you have high cholesterol.
Statins work to lower your LDL cholesterol and triglycerides and are very effective.
When you take a statin, your body breaks it down.
This is illegal and therefore, this would not be indicated on the label.
There is also a risk of contamination and incorrect claims.
Vitamin A Supplements
Vitamin A has many health benefits and is an essential fat-soluble vitamin.
This throw in of vitamin A is called preformed vitamin A.
This is different from beta-carotene that you’ll find in fruits and vegetables.
Combination Supplements
Some supplements on the market contain various ingredient combinations and are marketed to support healthy cholesterol levels.
These supplements may contain oil extracts, niacin and magnesium, to name a few.
Keep in mind that these supplements are targeted at consumers who already have healthy cholesterol levels.
Foods that contain soluble fiber include vegetables, fruits, legumes, oats and whole grains.
Fiber has a filling effect, too.
Eating more fiber can help you feel more satisfied from eating less, which may help support weight-loss efforts.
Consider limiting red meat to no more than twice per week, and choose leaner cuts when possible.
Choose lower-fat dairy products or simply use a smaller portion of the real deal.
Include sources ofunsaturated fatsin your diet to promote heart health, add flavor and help with feelings of fullness.
Avocado, nuts, seeds and olive oil are excellent sources of unsaturated fats.
Supplements can be contaminated, produce unwanted side effects, interfere with your medications and drain your wallet.
Small, sustainable changes can go a long way.
If you need assistance in sorting through supplements, discuss it with a registered dietitian or your medical provider.
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StatPearls Publishing; 2025.